Page 6 - Paws and Hooves - Autumn 2022

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Page 6 - Paws and Hooves - Autumn 2022
P. 6

New hyperthermic treatment




        for cancer in horses





                  ioneering technology empowers vets at RVC Equine to treat critically ill horses in
          P       revolutionary ways. Thanks to funding from the ACT, this specialist team can now treat

                  skin cancer using a new Thermofield device. When combined with chemotherapy injected
                  directly into the tumour, the heat generated by this device can help shrink tumours.


        Skin cancer is very common in       The teamֱs
        older grey horses. Itֱs estimated   first patient
        that more than 80% of grey           was a lovely
        horses, over the age of 15, will    16hh Irish
        have at least one melanoma          draught
        during their lifetime. Dr Michael   called Sylvia.
        Hewetson, a Senior Lecturer in      Poor Sylvia
        Equine Medicine at the RVC,          was riddled
        explains,                            with tumours
                                            and the
        ֱMelanocytes are normal              team quickly
        cells which affect skin              realised
        pigmentation. A gene                 they had a
        mutation in these type of           challenge on
                                             their hands.
        cells, gives grey horses            With large
        their characteristic coat            tumours all
        colour, but it comes at             around her tail
                                            and bottom,
        a terrible price because             she was
        they are prone to become             struggling to defecate or urinate   The team carefully assessed
        cancerous.ֱ                         and was very uncomfortable.          her case, and after discussions
                                            She also had tumours on both
                                                                                 with Sylviaֱs owner Christine,
        Equine melanoma is difficult to      sides of her head near her          they decided on a two-stage
        treat. Surgical removal              salivary glands.                                     treatment
        is most effective but                                                                      plan. The
        sadly tumours can be        How does it work?                                              first stage
        inoperable due to their                                                                    involved
        position or size. Human     1. A large volume of electromagnetic energy is transferred     treating all
        cancer treatment has        deep into the tissue.                                          the tumours
        combined hyperthermia                                                                       using the
        with chemotherapy           2. This gently heats the targeted area to therapeutic          Thermofield
        for many years and          temperatures that selectively kill cancerous cells without      device. The
        this has had positive       harming the surrounding healthy tissue.                         aim was to
        results, including          3. The heat makes chemotherapy more effective as it             shrink the
        reduced tumour size         increases the amount that can be absorbed...                    tumours
        and increased survival                                                                       enough
        times. Knowing this,        4. ...Plus it inhibits DNA repair in the cancerous cells.        so they
        RVC equine set out                                                                           could be
        to develop a new            5. Crucially this technique can be performed in standing         surgically
        treatment for equine        horses without the need for a general anaesthetic.               removed
        melanoma using the                                                                         later.
        Thermofield device.


        6                                                                              Paws & Hooves Autumn 2022
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